Aluminium chloride is used in regular antiperspirants. However, hyperhidrosis sufferers need solutions with a much higher concentration to effectively treat the symptoms of the condition. These antiperspirant solutions are especially effective for treatment of axillary hyperhidrosis. Normally it takes around three to five days to see the results. The main secondary effect is irritation of the skin. For severe cases of plantar and palmar hyperhidrosis there is some success using conservative measures such as aluminium chloride antiperspirants.
Injections of botulinum toxin type A, going by the brand name of Botox or Dysport, are used to disable the sweat glands.. The effects can last from 4â€“9 months depending on the site of injections. This procedure used for underarm sweating has been approved by the U.S. Food and Drug Administration (FDA).
Several anticholinergic drugs reduce hyperhidrosis. Oxybutynin (brand name Ditropan) is one that has shown promise. although it has important side effects, which include drowsiness, visual symptoms and dryness in the mouth and other mucous membranes. A time release version of the drug is also available (Ditropan XL), with purportedly reduced effectiveness. Glycopyrrolate (Robinul) is another drug used on an off-label basis. The drug seems to be almost as effective as oxybutynin and has similar side-effects. Other anticholinergic agents that have been tried include propantheline bromide (Probanthine) and benztropine (Cogentin).
Antidepressants and anxiolytics were formerly used on the belief that primary hyperhidrosis was related to an anxious personality style.
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